Sarcopenia, muscle loss with age, can we prevent it ?

 Sarcopenia

Sarcopenia is an aging-related disorder marked by a broad, progressive loss of skeletal muscle mass and strength along with a deterioration in physical performance that can lead to physical impairment. death and life quality are both low Sarcopenia affect people as they age, although its symptoms are comparable to those of illnesses like muscle underuse or malnutrition that afflict younger people.

Sacopee Nia is now seen as a serious health issue because it typically affects more women than males. Sarcopenia is characterized by age-related muscular atrophy and motor function decline. After the age of 30, muscular atrophy occurs at a rate of roughly 1% each year. It appears that lifestyle choices like inactivity and poor calorie and protein intake are related to this.

A decrease in anabolic hormones and an increase in inflammatory cytokines are also present.

Although atrophy was originally believed to be the primary cause of decreased muscular strength, it is now known that a variety of variables, including alterations to the connection of the central nervous system and skeletal muscles, are also to blame.

Muscles, such as muscular fiber denervation and increased irregularity of motor unit firing, may be a factor in the deteriorating muscle strength seen in sarcopenic individuals. Various aspects of muscle performance may also be impacted by additional factors, such as a decrease in blood supply to muscles with aging.

Muscle mass and muscle strength are evaluated as part of the clinical diagnosis of sarcopenia. Physical performance is measured using factors like gait speed. or chair rise time muscle mass can be assessed using a variety of techniques, such as dual energy x-ray absorption DEXA computed tomography.

Using a hand grip dynamometer, muscle strength can be measured during a CT or magnetic resonance imaging (MRI) scan. Sarcopenia is currently being treated with nutritional and physical therapies to decrease its progression. Because of the increased life expectancy around the world, pharmacologic approaches that target pro-anabolic and anti-catabolic processes as well as neuromuscular function are being researched as potential treatments for sarcopenia.