Can we determine how faster we are aging?
What is the difference
between age and aging?
We see people around us who look a lot younger, or a lot
older than their age. So obviously there is a difference in the pace of the aging process in all individuals. Can we determine this by looking at the grey
hair, or the wrinkles?
Is our aging normal or more than normal? What are the
possible indicators?
Can we assess our aging process by ourselves at home?
Yes, there
are some common ways, doctors suggest checking your aging process.
Why do
we age?
The very first and obvious outcomes of aging are
o
The calcination (deposition of calcium) in
arteries, joints, etc. Tissues and joints get stiff with age.
o
The loss of proteins, and muscle mass, resulting in
loss of muscle strength and leading to wrinkles formation. Loss of protein is
called sarcopenia. The overall condition of losing organ size because of loss
of protein, organelles, fat, etc. is called atrophy. The first muscle to be lost
is the muscle from the front part of the thigh.
o
Deterioration of bones. As a result, people
get shorter in old age.
Telomere
contraction:
·
What are
telomeres?
The telomeres are the ends of the chromosomes, present inside
all body cells. The chromosomes contain an individual's genetic information, in the form of DNA sequences highly and compactly coiled to make chromosomes. The ends
of the chromosomes are protected by a protein called telomeres. The analogy
commonly used to explain the telomeres is the ends of the shoe laces, the way
they are protected. Exactly the same way the chromosomal DNA is protected against
deterioration by these telomeres. There is an enzyme called telomerase enzyme
that promotes the synthesis of these telomere proteins.
The normal analogy used to explain telomere contraction and
aging is the photocopying of a paper. With every new photocopy, the text gets
blurred and blurred, after millions of copies, it may not be seen at all.
The same is the case with human cells. Cells are meant to
replicate and multiply as the child grows, when the growth stops body still makes
new cells. As different cells in the body have different ages, they need to be
replaced. Recovery from disease or healing of wounds also requires cell
division.
·
Cellular
senescence
The cell’s capability of replicating is known as senescence.
It reduces over time as more and more copies of cells are produced. And finally, cellular senescence stops.
·
How much
telomerase does the human body normally produce?
Our body is made up of two types of cells, the normal body
cells or somatic cells, that make up all our organs body tissues, bones,
muscles nerves, etc.
o
The germ cells are involved in the process of
reproduction. These cells are rich in producing the telomerase enzyme.
o
Our normal body cells do not produce telomerase
or produce in undetectable levels, but these levels are high in stem cells. Stem
cells are the cells that are the precursors to produce blood cells.
o
Cancer cells richly produce these telomerase
enzymes.
o
The placental cells in pregnant women also make
telomerase as it has to sustain and keep replicating the placental cells, till
the end of pregnancy.
How to determine aging by ourselves at home.
All the above-mentioned outcomes of aging lead to specific
symptoms
How can we test these symptoms?
o
The aging mainly affects the strength of
muscles, muscle mass is not counted. One simple test is to check your muscle
strength using the grip of the hand. You can use simple grip strength devices to
check your muscle strength.
A normal male must have 66pounds
equal to 30 Kg of strength. And a normal female may have a strength of 44
pounds or 20 kg.
o
Second is just to try to get up from the floor.
If you have sarcopenia, you may have to push yourself bend and roll over to
get up. It will take time and you cannot just stand up in one jerk.
Well, there are some indicators declared by the researchers
They include the
ones given below.
MRI
scans
As mentioned the size of the organs diminishes with age
because of the loss in mass of proteins, fats, and cell organelles. MRI scans can
help determine the size contraction for various organs caused by atrophy,
sarcopenia, etc. this can help figure out the aging process of a person.
Another method is to determine the telomere length contraction
in individuals to determine age.
Telomere
contraction:
The telomere contraction can be measured to give an idea
about the aging of a person.
DNA
methylation
DNA methylation is a process of the addition of a methyl group -CH3
to the DNA molecule that naturally occurs and helps turn on or turn off certain
genes in our DNA sequence. It explains the changes in physical of cognitive
human function with age and learning. The change in genes is the basis for modern epigenetic theory.
These changes can be determined as well LUMA or MRI scans can be used to determine these levels and help determine the age.
How
can we increase our longevity?
1. First thing
is to start taking vitamin D supplements. As discussed in detail in one of our
previous articles it D importance, vitamin D helps fight sarcopenia.
2. Resistance
training can help strengthen muscles and bones. We have discussed this in
detail in one of our previous articles that how putting your muscles, or bones
under stress can help revert the aging process.
3. Telomerase
enzymes are available in the market and they are reported to have positive impacts
on reversing age.
4. Folic acid
is another important type of amino acid, required for DNA. Its deficiency can
cause damage to DNA just like radiation. So take its supplements.
5. Fasting
is a way to increase the production of growth hormones. Secondly, it triggers autophagy, a mechanism that recycles older, less efficient body cells and helps
reverse aging.
6. Keeping
your cortisol levels low, means keeping yourself calm and avoiding stress. As
stress affects the process of maintaining and repairing body cells. reduce cortisol
7. Include
more proteins in your diet. As discussed before in our article on proteins, it’s mentioned,
which protein sources are best in terms of absorption into the bloodstream. 3 eggs
a day are the best source, even better than adding synthetic, expensive whey
proteins to your diet.
Which supplements available in the market can help slow down aging is discussed in detail in our article on anti-aging supplements.
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